A novel continuous subcutaneous lactate monitoring system☆
نویسندگان
چکیده
منابع مشابه
A novel continuous subcutaneous lactate monitoring system.
A novel continuous lactate monitoring system has been developed modifying the GlucoDay portable medical device (A. Menarini Diagnostics), already present in the European market, and used to continuously measure glucose levels. Lactate oxidase based biosensors have been developed immobilising the enzyme on nylon net and placing it on a Pt electrode. The biosensor was connected to the portable de...
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Blood lactate concentration is a highly sensitive measure of tissue oxygen deprivation from ischemia, trauma, and hemorrhage, which can produce life-threatening shock. Significantly, blood lactate is the most reliable end point indicator of resuscitation and predictor of survivability. The need for continuous measurement of blood lactate, and the slowness of discrete conventional photometric as...
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sayed by liquid chromatography, immunoassay, or capillary electrophoresis. The separation systems offer selective detection of analytes, but in many cases, the temporal resolution of the assay is not sufficient for continuous real-time monitoring of the microdialysate. These techniques are limited by the minimum sample volume required for practical sample handling and reliable measurements. The...
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OBJECTIVE To evaluate the accuracy of a new subcutaneous glucose sensor (Glucoday; A. Menarini Diagnostics) compared with venous blood glucose measurement in type 1 and type 2 diabetic patients. RESEARCH DESIGN A multicenter study was performed in 70 diabetic patients. A microdialysis fiber was inserted subcutaneously into the periumbelical region and perfused with a buffer solution. Glucose ...
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ژورنال
عنوان ژورنال: Biosensors and Bioelectronics
سال: 2005
ISSN: 0956-5663
DOI: 10.1016/j.bios.2004.10.031